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‡ Emotional symptoms results based on a published, 4-month, double-blind, placebo-controlled clinical trial: Winther K, Hedman C. Curr Ther Res Clin Exp. 2002;63(5):344-353.  Physical symptoms results based on various double-blind, placebo-controlled clinical trials: Winther K, Hedman C. Curr Ther Res Clin Exp. 2002;63(5):344-353. Gerhardsen G, et al.  Adv Ther. 2008;25(6):595-607, and Anton S, et al. Diabetes Technol Ther. 2008;10(5): 405-412.

ll Based on data from Winther K, et al. Climacteric. 2005;8:162-170 and Gerhardsen G, et al. Adv Ther. 2008;25(6):595–607.

§ Study's inclusion criteria did not stipluate women had diagnosis of PMS; rather, this study was conducted on healthy, overweight women.